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Manchester City vs Napoli Predictions | betCompare

Written by Boluwatitonisola Omoniyi | Sep 18, 2025 11:40:48 AM

These top European clubs are going to come up with an intense fixture. Manchester City are likely to secure a win against Napoli in their upcoming UEFA Champions League clash

Match info: UEFA Champions League

Venue: Etihad Stadium, Manchester

Date: Thursday, 18th September 2025

Time: 8 pm Nigerian time

Kevin De Bruyne will make a swift return to the Etihad Stadium when his new Napoli side travel to Manchester City for their opening League Phase fixture in the 2025-26 Champions League on Thursday night.

The two teams butt heads in Europe’s premier club competition for the first time since the 2017-18 group stage when the Citizens won both matches by an aggregate score of 6-3, including a 2-1 success at the Etihad.

Head-to-head:

  • Manchester City have won 2 of the 4 UEFA Champions League meetings between the two teams.
  • Napoli have recorded just 1 win.
  • The other clash ended in a draw.
  • The Cityzens scored 8 goals.
  • Napoli hit the back of the net on 6 occasions.
  • Manchester City are on a two-match winning streak against Gli Azzurri.
  • Napoli are on a three-match winning run.
  • The Cityzens have won two of their last four matches.
  • All their encounters produced at least 2 goals.
  • 3 of their 4 clashed produced at least 3 goals.

Form:

  • Manchester City in all competitions: W-L-L-W
  • Napoli in all competitions: W-W-W

Team News:

Rayan Cherki, Omar Marmoush, Mateo Kovacic and Rayan Ait Nouri are injured. They will be out of action for Manchester City. John Stones might also sit out due to a lack of fitness.
Napoli will be without the services of Romelu Lukaku, Amir Rrahmani and Nikita Contini. They are injured.

Player(s) to watch:

  • Erling Haaland is coming in after scoring a brace in the Manchester derby, which helped his side secure an easy win. The Norwegian forward looks in good touch and is going to be a menace to the opponent’s defence. Haaland is going to be one of the important men in the final third for the hosts.
  • Kevin De Bruyne is going to play an important role for SSC Napoli here. Kevin De Bruyne is an experienced star who was a part of Manchester City till last season. He can regulate the ball well in the midfield and can surely score goals. With the ball at his feet, he is going to create issues for the opponents.
  Man City Draw Atletico  GG/BTS Over 2.5 Under 2.5
1XBet 1.7 4.14 5.32 1.72 1.8 2.16
22Bet 1.64 3.98 5.1 1.72
1.74
2.09
WazoBet 1.7
3.8 4.8 1.71 1.73
2.07
BetWinner 1.64
3.98 5.1 1.72 1.74
2.09
Note: These are the odds at the time of publication.