Southampton vs Arsenal Predictions | betCompare

The Saints are potentially going to make things tougher for the visitors on home soil. The Gunners, with their fluid playing style, are surely going to create problems for the hosts. If Arsenal maintain their composure and control of possession, they might come out on top to secure a win against Southampton 

Match info: FA Cup

Venue: St. Mary's Stadium, Hampshire

Date: Saturday, 4^th April 2026

Time: 8 pm Nigerian time

Having had a fortnight to dwell on one dose of knockout misery, Arsenal seek a fresh start in Saturday's FA Cup quarter-final showdown with Southampton at St Mary's.

The Gunners made hard work of their fifth-round triumph over Mansfield Town, while the Saints edged out Fulham 1-0 to earn a date with the record 14-time winners.

Head-to-head:

• Southampton have won 23 of the 108 meetings between the two teams.

• Arsenal recorded 55 victories.

• The remaining 30 clashes ended in draws.

• Southampton are on a 14-match unbeaten run.

• Arsenal have secured three wins in their last five games.

• The Saints have only secured one win in their last five outings against the Gunners.

• Eight of their last 10 encounters produced at least 10 goals.

Form:

• Southampton in all competitions: W-D-W-W-W

• Arsenal in all competitions: W-D-W-W-L

Team News:

• Southampton will not have Mads Roerslev in action. He is injured. They might also miss out on Leo Scienza, Welington and Jay Robinson due to their fitness issues.

• Eberechi Eze and Mikel Merino are not going to be in action for Arsenal. They are injured and are likely to return in April-May 2026. Bukayo Saka, Martin Odegaard, Martin Zubimendi, Jurrien Timber, William Saliba, Gabriel Magalhaes, Leandro Trossard, Noni Madueke, Piero Hincapie and Declan Rice are not confirmed to be a part of the squad.

Player(s) to watch:

• Cyle Larin will be looking to step up his game so that he can help his side stand a chance against the Gunners. He was one of the goal scorers for Southampton in their last league outing. Cyle Larin is going to lead the attack from the front for the Saints and will be looking to come up with a top performance here.

• Viktor Gyokeres helped the Sweden national football team to secure a spot in the FIFA World Cup 2026 after a couple of strong performances during the recent international break. The 27-year-old will be looking to use this momentum for Arsenal now. He is going to be a constant threat to the opponent’s defence.